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Related Experiment Videos

Human BAC ends.

S Zhao1

  • 1The Institute for Genomic Research, 9712 Medical Center Drive, Rockville, MD 20850, USA. szhao@tigr.org

Nucleic Acids Research
|December 11, 1999
PubMed
Summary
This summary is machine-generated.

The Human BAC Ends database consolidates human BAC end sequences (BESs) and mapping data. This resource aids genomic research by integrating sequence, quality scores, and annotation for enhanced discovery.

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Area of Science:

  • Genomics
  • Bioinformatics

Background:

  • Human Genome Project generated vast amounts of sequence data.
  • Bacterial Artificial Chromosome (BAC) clones are crucial for mapping and sequencing large genomic regions.
  • BAC end sequences (BESs) provide valuable information for genome assembly and gene mapping.

Purpose of the Study:

  • To create a centralized, publicly accessible database of human BAC end sequences (BESs).
  • To integrate BESs with mapping data and sequence annotations for comprehensive analysis.
  • To facilitate efficient searching and retrieval of human genomic information.

Main Methods:

  • Compilation of non-redundant human BESs from major genomic research centers (TIGR, UW, CalTech).
  • Integration of BAC mapping data from various genome centers.

Related Experiment Videos

  • Annotation of BESs for repetitive elements, expressed sequence tags (ESTs), and sequence tagged sites (STSs).
  • Main Results:

    • The Human BAC Ends database provides access to curated human BESs.
    • Each entry includes sequence data, Phred quality scores, mapping information, and annotations.
    • The database offers links to external resources like GenBank, dbGSS, and GDB.

    Conclusions:

    • The Human BAC Ends database serves as a valuable resource for human genome research.
    • It enables efficient sequence and clone-based searches.
    • Free web accessibility and anonymous FTP support broad scientific utilization.