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A Protocol for Computer-Based Protein Structure and Function Prediction
Published on: November 3, 2011
The Protein Data Bank.
H M Berman1, J Westbrook, Z Feng
1Research Collaboratory for Structural Bioinformatics (RCSB), Rutgers University, Piscataway, NJ 08854-8087, USA. berman@rcsb.rutgers.edu
Nucleic Acids Research
|December 11, 1999
Summary
The Protein Data Bank (PDB) archives worldwide structural data for biological macromolecules. It details PDB goals, data systems, access information, and future development plans for this vital scientific resource.
Area of Science:
- Structural Biology
- Bioinformatics
- Biochemistry
Background:
- The Protein Data Bank (PDB) serves as the primary global repository for the structural data of biological macromolecules.
- Accurate and accessible structural data is fundamental for understanding biological processes at a molecular level.
Purpose of the Study:
- To outline the objectives and operational framework of the Protein Data Bank.
- To provide comprehensive information on data deposition, access, and user support.
- To communicate near-term developmental strategies for the PDB resource.
Main Methods:
- Description of data archiving and retrieval systems.
- Explanation of data deposition protocols and standards.
- Information dissemination strategies for users and stakeholders.
Main Results:
- Established the PDB as the definitive worldwide archive for macromolecular structural data.
- Detailed the established systems for data submission and user access.
- Outlined current information resources and future development trajectories.
Conclusions:
- The PDB is a critical, centralized resource for structural biology research.
- Efficient data management and accessibility are key to advancing molecular science.
- Ongoing development ensures the PDB remains a dynamic and essential scientific archive.
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