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Related Experiment Videos

REBASE - restriction enzymes and methylases.

R J Roberts1, D Macelis

  • 1New England BioLabs, Inc., 32 Tozer Road, Beverly, MA 01915, USA. roberts@neb.com

Nucleic Acids Research
|December 11, 1999
PubMed
Summary
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REBASE is a comprehensive restriction enzyme database. It includes data on enzymes, DNA methyltransferases, and related proteins, aiding molecular biology research.

Area of Science:

  • Molecular Biology
  • Genomics
  • Bioinformatics

Background:

  • Restriction enzymes and related proteins are crucial tools in molecular biology.
  • Databases are essential for organizing and accessing complex biological information.

Purpose of the Study:

  • To provide a comprehensive and up-to-date resource for restriction enzymes and related proteins.
  • To consolidate diverse data, including recognition sites, commercial availability, and genomic predictions.

Main Methods:

  • Compilation of published and unpublished literature.
  • Inclusion of data from genomic sequence analysis.
  • Data organization and distribution via web and FTP servers.

Main Results:

Related Experiment Videos

  • REBASE offers extensive information on restriction enzymes, DNA methyltransferases, and associated proteins.
  • The database includes recognition/cleavage sites, isoschizomers, methylation sensitivity, and structural data.
  • Newly predicted enzymes from genomic sequences are now integrated.

    • Conclusions:

    • REBASE serves as a vital, centralized hub for researchers working with restriction enzymes and related proteins.
    • The database facilitates access to a wide array of critical data for diverse biological applications.