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MEROPS: the peptidase database.

N D Rawlings1, A J Barrett

  • 1MRC Molecular Enzymology Laboratory, The Babraham Institute, Babraham, Cambridgeshire CB2 4AT, UK. neil.rawlings@bbsrc.ac.uk

Nucleic Acids Research
|December 11, 1999
PubMed
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The MEROPS database now includes sequence alignments and cladograms for peptidase families. These updates aid in differentiating known enzyme variants from novel peptidases.

Area of Science:

  • Biochemistry
  • Bioinformatics
  • Genomics

Background:

  • The MEROPS database is a key resource for peptidase information.
  • Distinguishing between species variants and novel peptidases is challenging.

Purpose of the Study:

  • To report significant updates to the MEROPS database.
  • To enhance the classification of peptidase sequences.

Main Methods:

  • Inclusion of sequence alignments for peptidase families.
  • Generation of cladograms for peptidase families.

Main Results:

  • The MEROPS database has been expanded with new data.
  • Sequence alignments and cladograms facilitate peptidase identification.

Related Experiment Videos

  • These tools aid in distinguishing species variants from novel enzymes.

    • Conclusions:

    • The updated MEROPS database provides valuable tools for peptidase research.
    • Enhanced classification improves understanding of peptidase diversity.