Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

InBase, the Intein Database.

F B Perler1

  • 1New England BioLabs, Inc., 32 Tozer Road, Beverly, MA 01915, USA. perler@neb.com

Nucleic Acids Research
|December 11, 1999
PubMed
Summary
This summary is machine-generated.

Inteins are protein splicing elements that perform self-catalytic reactions. InBase is a comprehensive online database detailing intein information, comparisons, and references.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Rescue of protein splicing activity from a Magnetospirillum magnetotacticum intein-like element.

Biochemical Society transactions·2004
Same author

Protein splicing and its applications.

Genetic engineering·2001
Same author

Hyperthermophilic inteins.

Methods in enzymology·2001
Same author

An alternative protein splicing mechanism for inteins lacking an N-terminal nucleophile.

The EMBO journal·2000
Same author

Protein splicing and its applications.

Current opinion in biotechnology·2000
Same author

Protein splicing in the absence of an intein penultimate histidine.

The Journal of biological chemistry·2000
Same journal

Correction to 'scSuperAnnotator: A platform for benchmarking comparison and visualizing automated cellular annotation methods for scRNA-seq data'.

Nucleic acids research·2026
Same journal

Correction to 'Differentiable partition function calculation for RNA'.

Nucleic acids research·2026
Same journal

Deployment of non-canonical splicing in tunicate genomes is mediated by divergent U2AF function and changing m6A modification in U1 and U6 snRNA.

Nucleic acids research·2026
Same journal

Bacillus subtilis DnaB forms multiple protein-protein interactions essential for DNA replication initiation.

Nucleic acids research·2026
Same journal

Multiple forms of protein-protein and DNA binding are exhibited by BrxC from the BREX phage restriction system.

Nucleic acids research·2026
Same journal

Biosynthesis of glycosylated 5-hydroxycytosine in the DNA of diverse viruses.

Nucleic acids research·2026
See all related articles

Area of Science:

  • Biochemistry
  • Molecular Biology
  • Bioinformatics

Background:

  • Inteins are protein sequences that catalyze their own excision and ligation of flanking protein sequences (exteins).
  • Understanding intein function is crucial for protein engineering and biotechnology applications.

Purpose of the Study:

  • To introduce InBase, a comprehensive online resource for intein information.
  • To provide a centralized repository for data on known inteins and their properties.

Main Methods:

  • Development of a curated online database (InBase) accessible via a web interface.
  • Inclusion of the Intein Registry within InBase.
  • Data compilation including general information, specific intein details, comparative tables, and bibliographies.

Related Experiment Videos

Main Results:

  • InBase serves as a comprehensive online resource for intein data.
  • The database includes the Intein Registry, offering a centralized catalog of inteins.
  • Detailed information, comparative analyses, and extensive bibliographies are provided for each intein.

Conclusions:

  • InBase enhances accessibility to intein knowledge for researchers.
  • The database facilitates comparative studies and further research into intein mechanisms and applications.
  • This resource supports advancements in protein splicing research and biotechnology.