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Guidelines for Elective Pediatric Fiberoptic Intubation
Published on: January 17, 2011
Amnestic agents in pediatric bronchoscopy
1Critical Care Medicine Department, Warren G. Magnuson Clinical Center, National Institutes of Health, Bethesda, MD 20892-1662, USA.
Insights
Pediatric fiberoptic bronchoscopy is safe, but anesthetic choice impacts complications in young children and those with HIV. Careful selection of sedation and analgesia is crucial for this patient population.
Area of Science:
- Pediatric critical care medicine
- Anesthesiology
- Pulmonology
Background:
- Fiberoptic bronchoscopy is a common diagnostic tool in pediatrics.
- Sedation and analgesia are frequently used to facilitate pediatric procedures.
- Assessing complication risks associated with these techniques is vital.
Purpose of the Study:
- To evaluate the risk of complications associated with sedation and analgesia during pediatric fiberoptic bronchoscopy.
- To identify factors influencing complication rates in this procedure.
Main Methods:
- Retrospective case series of 103 fiberoptic bronchoscopies in 64 pediatric patients (1-18 years).
- Data collected via chart review, including anesthetic agents, dosages, procedure duration, and complications.
- Complications included oxygen desaturations, vital sign alterations, and emergence reactions.
Main Results:
- Complications occurred in 13 procedures (12.6%).
- Oxygen desaturations, stridor, cough, apnea, and nasal bleeding were noted.
- Complications were more frequent in children under 3 years old and those with HIV infection.
Conclusions:
- Pediatric fiberoptic bronchoscopy is generally safe and effective.
- Anesthetic selection significantly impacts complication rates in specific pediatric subsets.
- Particular caution is advised for children under 3 years and those with HIV.
Study Objective:
To assess the risk for complications with the use of sedation and analgesia techniques in pediatric fiberoptic bronchoscopy.
Design:
A retrospective case series.
Setting:
The ICU of a 325-bed tertiary care research hospital.
Patients:
Patients from 1 to 18 years of age who underwent fiberoptic bronchoscopy with BAL or transbronchial biopsy between June 1991 and December 1995 and received IV sedation and analgesia.
Interventions:
None.
Methods:
A retrospective chart review was performed. Extracted data included anesthetics and sedatives used and their per kilogram dosages, procedure durations, and complications including oxygen desaturations < 90%, vital sign alterations that required intervention, and emergence reactions to ketamine.
Results:
A total of 103 bronchoscopies were performed on 64 patients. Ketamine was used as the primary anesthetic in 60 procedures (58%). A combination of fentanyl and midazolam was used in 38 of the 43 remaining procedures. A variety of combinations were used in the five remaining procedures. Complications occurred in 13 procedures and included oxygen desaturations, stridor, cough, apnea, and nasal bleeding. Twelve of the 13 complications occurred in patients with a diagnosis of HIV infection. Eight of the13 complications involved children < or = 3 years of age.
Conclusions:
Pediatric bronchoscopy is a safe and valuable procedure. However, in this study, anesthetic selection was shown to adversely affect the complication rate in the subsets of children < or = 3 years of age and with an underlying diagnosis of HIV infection.
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