Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Epidermal maturation arrest.

A T Jaffe1, W R Heymann, N Lawrence

  • 1University of Medicine and Dentistry of New Jersey, Robert Wood Johnson Medical School at Camden, Cooper Health System, USA.

Dermatologic Surgery : Official Publication for American Society for Dermatologic Surgery [Et Al.]
|December 14, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

An acute, ulcerative, sarcoidal tattoo reaction following SARS-CoV-2 mRNA-1273 vaccination.

Dermatology online journal·2022
Same author

Functional modulation of the human voltage-gated sodium channel Na<sub>V</sub>1.8 by auxiliary β subunits.

Channels (Austin, Tex.)·2020
Same author

Development of a core outcome set for cutaneous squamous cell carcinoma trials: identification of core domains and outcomes.

The British journal of dermatology·2020
Same author

Nonmelanoma skin cancer in women.

International journal of women's dermatology·2019
Same author

Growth, structure, spectral and optical properties of semiorganic crystal: Pyridine-1-ium-2-carboxylatehydrogenbromide.

Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy·2015
Same author

Prefrontal cortex markers of suicidal vulnerability in mood disorders: a model-based structural neuroimaging study with a translational perspective.

Translational psychiatry·2015
Same journal

A Comprehensive Review of Dermal Fillers and Biostimulators for Neck Rejuvenation.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]·2026
Same journal

Extramammary Paget Disease: A Single-Center, Clinical Analysis.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]·2026
Same journal

Surgical Interventions for the Treatment of Hidradenitis Suppurativa: A Systematic Review of Surgical Impact on DLQI.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]·2026
Same journal

Optimization and Prevention of Error in Surgical Site Identification.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]·2026
Same journal

Endovenous Laser Ablation of Supratrochlear Forehead Veins: 10-Year Experience.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]·2026
Same journal

Laser-Assisted Drug Delivery of 5-Fluorouracil and Triamcinolone vs. Triamcinolone Monotherapy Does Not Lead to Different Outcomes in the Treatment of Burn Hypertrophic Scars.

Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.]·2026
See all related articles

Delayed wound healing in patients undergoing Mohs surgery may be resolved with topical steroids or ibuprofen. These treatments target inflammatory pathways that can impede epidermal maturation and promote faster skin repair.

Area of Science:

  • Dermatology
  • Wound Healing Research
  • Surgical Pathology

Background:

  • Cutaneous wound repair is a complex process involving cytokines, blood components, extracellular matrix, and cells.
  • Normal healing can be disrupted by various factors at any stage.

Observation:

  • Four cases of abnormal wound repair after Mohs micrographic surgery are presented.
  • Patients exhibited delayed healing and arrested epidermal maturation when wounds healed by second intention.

Findings:

  • Topical steroids and/or ibuprofen were effective in treating these cases of delayed wound healing.
  • Therapy aimed to inhibit the arachidonic acid cascade or other cytokines hindering epidermal differentiation.

Implications:

Related Experiment Videos

  • This suggests a potential therapeutic approach for specific wound healing complications.
  • Understanding cytokine involvement may offer new strategies for enhancing epidermal reconstitution in surgical wounds.