Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

To stent or not to stent.

C Schalcher1, G Sütsch, F W Amann

  • 1Department of Internal Medicine, University Hospital, Zurich.

Schweizerische Medizinische Wochenschrift
|December 14, 1999
PubMed
Summary

Coronary artery stenting improves outcomes for percutaneous revascularization, reducing restenosis in large vessels. While in-stent restenosis persists, stenting offers better long-term results than conventional PTCA, with adjunctive therapies further improving safety.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Exercise-induced left arm pain and thrombocytosis].

Praxis·2005
Same author

LEOPARD syndrome: cardiac imaging findings.

AJR. American journal of roentgenology·2005
Same author

[Coronary stents].

Therapeutische Umschau. Revue therapeutique·2003
Same author

[Medicamentous management of acute coronary syndrome without ST segment elevation].

Therapeutische Umschau. Revue therapeutique·2002
Same author

Rationale and perspective of endothelin-1 antagonism in acute heart failure.

Journal of cardiovascular pharmacology·2002
Same author

The dual endothelin receptor antagonist tezosentan acutely improves hemodynamic parameters in patients with advanced heart failure.

American heart journal·2001

Area of Science:

  • Cardiology
  • Interventional Cardiology
  • Vascular Medicine

Background:

  • Coronary artery stenting has significantly improved outcomes in percutaneous revascularization procedures.
  • Stenting is particularly effective in reducing restenosis in coronary arteries larger than 3 mm in diameter.

Purpose of the Study:

  • To evaluate the efficacy and safety of coronary artery stenting compared to conventional Percutaneous Transluminal Coronary Angioplasty (PTCA).
  • To discuss adjunctive pharmacological treatments and novel approaches for managing in-stent restenosis and improving procedural outcomes.

Main Methods:

  • Review of clinical evidence on coronary artery stenting versus conventional PTCA.
  • Analysis of the impact of adjunctive therapies like aspirin, clopidogrel, and GP IIb/IIIa inhibitors.
  • Consideration of emerging technologies and future research directions, including brachytherapy and molecular approaches.

Main Results:

  • Stenting reduces restenosis in large vessels and offers better long-term results than PTCA, despite persistent in-stent restenosis.
  • Combination therapy with aspirin and clopidogrel, along with improved deployment techniques, has decreased subacute stent thrombosis.
  • GP IIb/IIIa inhibition shows promise in reducing ischemic events related to both stenting and PTCA.

Conclusions:

  • Coronary artery stenting is a valuable tool in percutaneous revascularization, offering improved long-term outcomes.
  • Medical therapy, including lipid-lowering agents and risk factor control, remains crucial for managing underlying coronary artery disease and delaying progression.
  • Future research into novel devices and molecular approaches may further refine treatment strategies for in-stent restenosis.

Related Experiment Videos