Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Parathyroidectomy: new criteria for evaluating outcome.

G L Irvin1, A S Molinari, D M Carneiro

  • 1Department of Surgery, University of Miami/Jackson Memorial and Veterans Affairs Medical Centers, Florida, USA.

The American Surgeon
|December 22, 1999
PubMed
Summary

Post-parathyroidectomy care requires updated biochemical monitoring. New criteria help identify patients with elevated parathyroid hormone (PTH) or calcium levels, indicating potential recurrence of hyperparathyroidism.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Deviations from Born-Oppenheimer theory in structural chemistry: Jahn-Teller, pseudo Jahn-Teller, and hidden pseudo Jahn-Teller effects in C3H3 and C3H3(-).

The journal of physical chemistry. A·2013
Same author

Production of a boraphosphene (RB:PR') in the vapor phase by thermolysis of a sterically encumbered diphosphadiboretane.

Journal of the American Chemical Society·2011
Same author

A novel electron-conformational approach to molecular modeling for QSAR by identification of pharmacophore and anti-pharmacophore shielding.

SAR and QSAR in environmental research·2011
Same author

Intra-operative parathyroid hormone monitoring in patients with parathyroid cancer.

Annals of surgical oncology·2007
Same author

"Limited" parathyroidectomy in geriatric patients.

Annals of surgery·2001
Same author

Improved electron-conformational method of pharmacophore identification and bioactivity prediction. Application to angiotensin converting enzyme inhibitors.

Journal of chemical information and computer sciences·2000

Area of Science:

  • Endocrinology
  • Surgical Oncology

Background:

  • Successful parathyroidectomy improves symptoms in primary hyperparathyroidism patients.
  • Evolving diagnostic methods for parathyroid hormone (PTH) and serum calcium necessitate revised postoperative outcome evaluation.

Purpose of the Study:

  • To establish revised biochemical criteria for assessing long-term outcomes after parathyroidectomy.
  • To identify patients at risk for recurrent hyperparathyroidism post-surgery.

Main Methods:

  • A retrospective analysis of 271 patients following parathyroidectomy over an average of 6.3 years.
  • Monitoring of serum calcium and intact parathyroid hormone (iPTH) levels.

Main Results:

  • 15% of patients with normal postoperative calcium had elevated iPTH.

Related Experiment Videos

  • Recurrent hyperparathyroidism was observed in 57% of patients with elevated calcium and iPTH.
  • 5 patients experienced hypercalcemia with normal iPTH levels.

    • Conclusions:

    • Annual monitoring of serum calcium and PTH is recommended for patients with successfully treated primary hyperparathyroidism.
    • Elevated iPTH in normocalcemic patients warrants attention.
    • These updated criteria aid in detecting late recurrence and managing hyperfunctioning parathyroid glands.