[Chordoma]
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1N. N. Blokhin Cancer Research Center, Moscow.
Arkhiv Patologii
|December 22, 1999
Abstract:
Chordoma is characterized clinicomorphologically and epidemiologically using own observations for 1955-1995 and literature data. Chordoma is a rare tumor. Its histogenetic association with the notochorda remnants and location in the region of axial skeleton results in a grave clinical course due to alteration of nervous structures of the brain and spinal cord. The diagnosis is based on roentgenological data showing the connection of the tumor with axial skeleton (in sacral-coccygeus and occipital-basilar regions in 90% of cases) and on typical histologic structure.
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