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Human Neuroendocrine Tumor Cell Lines as a Three-Dimensional Model for the Study of Human Neuroendocrine Tumor Therapy
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Resistance to several steroids in two sisters.

M I New1, S Nimkarn, D D Brandon

  • 1Department of Pediatrics, New York-Presbyterian Hospital, New York Weill Cornell Center, 10021, USA. minew@mail.med.cornell.edu

The Journal of Clinical Endocrinology and Metabolism
|December 22, 1999
PubMed
Summary

This study identifies a rare genetic condition in a young Native American girl exhibiting partial resistance to multiple steroid hormones, including glucocorticoids, mineralocorticoids, and androgens. This finding suggests a potential coactivator defect affecting steroid hormone action.

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