Effects of dietary composition and exercise timing on substrate utilization and sympathoadrenal function in healthy...

The effects of dietary composition (high-fat [FAT] or high-carbohydrate [CHO]) and exercise timing (preprandial exercise [Ex-] or postprandial exercise [-Ex]) on postprandial substrate utilization and sympathoadrenal function were studied in seven women aged 20 to 21 years. The experimental protocol included four different sessions (Ex-FAT, FAT-Ex, Ex-CHO, and CHO-Ex). The FAT and CHO diets provided 48% and 5% fat, respectively. On the experimental days, subjects ate a meal containing the same caloric energy at lunchtime, and they exercised for 30 minutes on a bicycle ergometer at an intensity of 60% maximal oxygen consumption (VO2max) before and after the meal, followed by rest for 3 hours. The resting respiratory quotient (RQ) was significantly lower (P < .05) with the FAT diet or postprandial exercise. The mean RQ during the experimental period was 0.78, 0.75, 0.81, and 0.77 in Ex-FAT, FAT-Ex, Ex-CHO, and CHO-Ex groups, respectively. The total area under the curve of serum norepinephrine (NE) as an index of NE secretion was significantly higher (P < .05) with the FAT diet or postprandial exercise (130.2, 175.8, 33.0, and 136.9 ng x mL(-1) x min, respectively). A negative correlation was observed between the RQ and the total area of NE (r = .49, P < .05). The serum thyroid hormone level was not influenced by dietary composition and exercise timing. These results suggest that postprandial exercise, especially after intake of a FAT diet, increases fat utilization via a slightly larger decrease in the RQ. This might be related to the sympathoadrenal system at rest and during exercise.