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Reward linked to increased natural killer cell activity in rats
M Wenner1, N Kawamura, T Ishikawa
1Department of Immunology, National Institute of Neuroscience, Tokyo, Japan. macwenner@hotmail.com
Neuroimmunomodulation
|December 22, 1999
Abstract:
In rats splenic natural killer (NK) cell activity was found to be significantly higher following chronic uncontrollable electrical stimulation of the lateral hypothalamus in fully conscious rats, compared to sham-operated rats. In a pre-test study, all rats had demonstrated that the electrode site had self-stimulating properties, which supports the possibility that the experience of reward may be implicated in NK cell activity augmentation.