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Preparation of a Corannulene-functionalized Hexahelicene by Copper(I)-catalyzed Alkyne-azide Cycloaddition of Nonplanar Polyaromatic Units
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A Stereospecific, Intermolecular Biaryl-Coupling Approach to Korupensamine A En Route to the Michellamines

Lipshutz1, Keith

  • 1Department of Chemistry, University of California, Santa Barbara, CA 93106 (USA).

Angewandte Chemie (International Ed. in English)
|December 22, 1999
PubMed
Summary

This study demonstrates complete control over axial chirality in Suzuki biaryl cross-coupling reactions using a strategically placed internal ligand. This method yields a single biaryl atropisomer, crucial for synthesizing complex molecules like korupensamine A.

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