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Related Experiment Videos

The relationship between phalangeal bone density and vertebral deformities.

R G Versluis1, H Petri, F J Vismans

  • 1Department of General Practice, Leiden University Medical Centre, PO-box 2088, 2301 CB Leiden, The Netherlands.

Calcified Tissue International
|December 22, 1999
PubMed
Summary

Radiographic absorptiometry (RA) of the phalanges offers a reliable method for assessing bone mineral density (BMD). This technique shows a strong correlation with vertebral deformities, comparable to hip bone density measurements.

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Area of Science:

  • Gerontology
  • Orthopedics
  • Radiology

Background:

  • Bone mineral density (BMD) measurement is crucial for assessing fracture risk.
  • Radiographic absorptiometry (RA) of the phalanges is a convenient and accessible method for BMD assessment.
  • Vertebral deformities are significant indicators of osteoporosis and fracture risk.

Purpose of the Study:

  • To evaluate the relationship between phalangeal BMD measured by RA and the presence of vertebral deformities in postmenopausal women.
  • To compare the efficacy of RA with dual-energy X-ray absorptiometry (DXA) of the hip in identifying vertebral deformities.
  • To assess the utility of RA in predicting fracture risk.

Main Methods:

  • A population-based cohort of 389 postmenopausal women (aged 55-84) was studied.

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  • Bone mineral density was measured using RA of the phalanges and DXA of the hip.
  • Vertebral deformities were assessed using lateral spine X-rays and vertebral morphometry.

    • Main Results:

    • Women with severe vertebral deformities (grade II) had significantly lower phalangeal and femoral neck BMD.
    • RA showed an odds ratio of 1.5 (95% CI: 1.1-2.1) for severe vertebral deformities, while DXA showed 1.3 (95% CI: 0.9-1.9).
    • Phalangeal BMD demonstrated a relationship with vertebral deformities comparable to femoral neck BMD.

    Conclusions:

    • Phalangeal BMD measured by RA is a reliable indicator of vertebral deformities in postmenopausal women.
    • RA can be a valuable tool for evaluating fracture risk, particularly when DXA equipment is unavailable.
    • RA provides a practical alternative for bone density assessment and fracture risk evaluation.