Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Videos

Rathke's cleft cyst with pituitary apoplexy: case report.

H Nishioka¹, H Ito, T Miki

¹Department of Neurosurgery, Tokyo Medical University, 6-7-1 Nishishinjuku, Shinjuku-ku, Tokyo 160-0023, Japan.

|December 22, 1999

Summary

A rare case of Rathke's cleft cyst presented as pituitary apoplexy, causing sudden headache and vision loss. The cyst, initially showing a hematoma, spontaneously regressed on MRI scans.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Visual and infrared input to the same dendrite in the tectum opticum of the python, Python regius: electron-microscopic evidence.

Brain research·1992

Same author

Intracellular protons inhibit inward rectifier K+ channel of guinea-pig ventricular cell membrane.

Pflugers Archiv : European journal of physiology·1992

Same author

Isolation and characterization of type 1 fimbriae from a chicken pathogenic Escherichia coli serotype O78.

The Journal of veterinary medical science·1992

Same author

Characterization of YM060, a potent and selective 5-hydroxytryptamine3 receptor antagonist, in rabbit nodose ganglion and N1E-115 neuroblastoma cells.

The Journal of pharmacology and experimental therapeutics·1992

Same author

[Clinical study on the time courses of serum myosin light chain I levels in patients with acute myocardial infarction: effect of intracoronary thrombolysis on serum myosin light chain I levels].

Kaku igaku. The Japanese journal of nuclear medicine·1992

Same author

Frequent amplification of the c-met gene in scirrhous type stomach cancer.

Biochemical and biophysical research communications·1992

Area of Science:

Endocrinology
Neurosurgery
Radiology

Background:

Rathke's cleft cysts are typically benign cystic lesions arising from remnants of the Rathke's pouch.
Pituitary apoplexy is a clinical syndrome characterized by sudden onset of severe headache, visual impairment, and ophthalmoplegia, usually due to pituitary infarction or hemorrhage.

Observation:

A 46-year-old woman presented with acute headache and visual loss, indicative of pituitary apoplexy.
Magnetic resonance imaging (MRI) revealed a cystic lesion between the anterior and posterior pituitary lobes with internal high-signal intensity, consistent with a hematoma.
Serial imaging demonstrated spontaneous regression of the lesion over three weeks.

Findings:

The patient's symptoms and imaging findings were attributed to a Rathke's cleft cyst complicated by a pituitary apoplectic event.

Related Experiment Videos

Histopathological examination following trans-sphenoidal surgery confirmed the presence of a Rathke's cleft cyst containing a hematoma.

Implications:

This case highlights an unusual presentation of Rathke's cleft cyst, emphasizing the importance of considering this diagnosis in pituitary apoplexy.
The spontaneous regression observed suggests a potential natural course for some Rathke's cleft cysts with intralesional hemorrhage.
Understanding such rare presentations aids in accurate diagnosis and management of sellar region pathologies.