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Dynamic contrast-enhanced subtraction MR angiography in intracranial vascular abnormalities
K Takano1, H Utsunomiya, H Ono
1Department of Radiology, Fukuoka University Chikushi Hospital, 377-1 Oaza Zokumyoin, Chikushino 818-8502, Japan.
Abstract:
We present our clinical experience with dynamic contrast-enhanced MR angiography (MRA) with subtraction for assessing intracranial vascular abnormalities. Ten patients with various cerebrovascular disorders underwent dynamic contrast-enhanced MRA on a 1.0-T system. Thirty sections (2 mm) were acquired in 29-30 s. Maximum intensity projection images and subtracted source images were compared with those obtained by conventional angiography. In all cases, the presence or absence of abnormalities in the targeted vessels, as well as the morphology of the sagittal sinuses, was clearly visualized as in conventional angiography, without any obstructions such as hyperintense hematomas or thrombi, or intraluminal turbulence. Although the temporal and spatial resolutions with current hardware are insufficient, these preliminary results suggest that dynamic contrast-enhanced MRA with subtraction may be useful for assessing vascular lesions with hemorrhage or thrombus, and the dural sinuses.
Insights
Dynamic contrast-enhanced MR angiography (MRA) with subtraction effectively visualizes intracranial vascular abnormalities and dural sinuses. This technique shows promise for assessing lesions, even with hemorrhage or thrombus.
Area of Science:
- Neuroradiology
- Vascular Imaging
- Magnetic Resonance Imaging
Background:
- Intracranial vascular abnormalities require accurate diagnostic imaging.
- Conventional angiography has limitations, including invasiveness.
- Magnetic resonance angiography (MRA) offers a non-invasive alternative.
Purpose of the Study:
- To evaluate the clinical utility of dynamic contrast-enhanced MRA with subtraction for intracranial vascular assessment.
- To compare the diagnostic performance of this MRA technique with conventional angiography.
Main Methods:
- Ten patients with cerebrovascular disorders underwent dynamic contrast-enhanced MRA on a 1.0-T system.
- High-resolution imaging (30 sections, 2 mm) was acquired rapidly (29-30 s).
- Maximum intensity projection and subtracted source images were analyzed and compared to conventional angiography.
Main Results:
- Dynamic contrast-enhanced MRA with subtraction clearly visualized vascular abnormalities and sagittal sinus morphology in all patients.
- The technique successfully identified lesions without obstruction from hematomas, thrombi, or turbulent flow.
- Diagnostic clarity was comparable to conventional angiography.
Conclusions:
- Dynamic contrast-enhanced MRA with subtraction is a promising technique for evaluating intracranial vascular lesions, including those with hemorrhage or thrombus.
- The method provides clear visualization of dural sinuses.
- Further hardware improvements in temporal and spatial resolution could enhance its utility.