A genetic dissection of the retinoid signalling pathway in the mouse
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Published on: December 27, 2024
M Mark1, N B Ghyselinck, O Wendling
1Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, C.U. de Strasbourg, France.
The Proceedings of the Nutrition Society
|December 22, 1999
Abstract:
To determine the functions of retinoic acid receptors RAR and RXR, we have systematically knocked-out their genes by homologous recombination in the embryonic stem cells and generated null-mutant mice. This approach has allowed us to perform a genetic dissection of the retinoic acid signalling pathway.
