Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Cancer-associated retinopathy.

S M Goldstein1, N A Syed, A H Milam

  • 1Department of Ophthalmology, Scheie Eye Institute and the Hospital of the University of Pennsylvania, Philadelphia, USA.

Archives of Ophthalmology (Chicago, Ill. : 1960)
|December 22, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Growth and Nutritional Outcomes in Children Post-Haematopoietic Stem Cell Transplant without Exposure to Total Body Irradiation.

Clinical oncology (Royal College of Radiologists (Great Britain))·2022
Same author

<i>In-vitro</i> cytotoxicity and cellular uptake studies of luminescent functionalized core-shell nanospheres.

Saudi journal of biological sciences·2017
Same author

Transition of childhood cancer survivors to adult care: The survivor perspective.

Pediatric blood & cancer·2017
Same author

Chiral nanoscale pores created during the surface explosion of tartaric acid on Cu(111).

Chemical communications (Cambridge, England)·2016
Same author

Influence of step faceting on the enantiospecific decomposition of aspartic acid on chiral Cu surfaces vicinal to Cu{111}.

Chemical communications (Cambridge, England)·2016
Same author

Feral Swine Leptospira Seroprevalence Survey in Hawaii, USA, 2007-2009.

Zoonoses and public health·2016
Same journal

The economics of the initial preventive physical examination in medicare-reply.

Archives of ophthalmology (Chicago, Ill. : 1960)·2013
Same journal

Modification of silicone oil retention sutures in aphakic eyes with iris loss-reply;.

Archives of ophthalmology (Chicago, Ill. : 1960)·2013
Same journal

December 2011 archives web quiz winner.

Archives of ophthalmology (Chicago, Ill. : 1960)·2013
Same journal

Angle involvement and glaucoma in patients with biopsy-proven iris melanoma: a response-reply.

Archives of ophthalmology (Chicago, Ill. : 1960)·2013
Same journal

About this journal.

Archives of ophthalmology (Chicago, Ill. : 1960)·2013
Same journal

In memoriam: goodwin m. Breinin, MD (1918-2011).

Archives of ophthalmology (Chicago, Ill. : 1960)·2013
See all related articles

Cancer-associated retinopathy is a rare cause of vision loss in cancer patients. This study links recoverin antibodies to a specific cancer type, aiding diagnosis and understanding of this rare paraneoplastic syndrome.

Area of Science:

  • Ophthalmology
  • Oncology
  • Immunology

Background:

  • Systemic cancer can manifest with ocular symptoms, primarily metastases or treatment side effects.
  • Paraneoplastic syndromes, including cancer-associated retinopathy, are infrequent causes of ophthalmic complaints.

Observation:

  • A patient with a malignant mixed mullerian tumor presented with cancer-associated retinopathy.
  • Serum analysis revealed circulating antibodies to recoverin in the patient.
  • Tumor cells were found to be positive for recoverin.

Findings:

  • The study identified a direct link between malignant mixed mullerian tumors and cancer-associated retinopathy.
  • Presence of recoverin antibodies and recoverin-positive tumor cells were key diagnostic markers.
  • This case highlights an uncommon paraneoplastic presentation.

Related Experiment Videos

Implications:

  • Understanding the pathophysiology of recoverin antibody-associated retinopathy can improve early diagnosis in cancer patients.
  • This finding may lead to novel therapeutic strategies targeting paraneoplastic autoimmune responses.
  • Further research into recoverin's role in tumorigenesis and autoimmune disease is warranted.