Cancer-associated retinopathy
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Updated: Oct 18, 2026

Retinal Vascular Reactivity as Assessed by Optical Coherence Tomography Angiography
Published on: March 26, 2020
S M Goldstein1, N A Syed, A H Milam
1Department of Ophthalmology, Scheie Eye Institute and the Hospital of the University of Pennsylvania, Philadelphia, USA.
Abstract:
Patients with systemic cancer may have a variety of ocular complaints. Most commonly these are metastases or adverse effects of therapy. Paraneoplastic syndromes, like cancer-associated retinopathy, rarely cause ophthalmic symptoms. We describe a patient with a malignant mixed mullerian tumor and cancer-associated retinopathy who had circulating serum antibodies to recoverin and cells positive for recoverin in the tumor. We discuss the typical clinical symptoms as well as the pathophysiology of this uncommon disorder.
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