Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Modeling prostate cancer distributions.

H Frimmel1, L Egevad, E Bengtsson

  • 1Centre for Image Analysis, Uppsala, Sweden.

Urology
|December 22, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

MR-guided adaptive versus ITV-based stereotactic body radiotherapy for hepatic metastases (MAESTRO): a randomized controlled phase II trial.

Radiation oncology (London, England)·2022
Same author

Percentage grade 4 tumour predicts outcome for prostate adenocarcinoma in needle biopsies from patients with advanced disease: 10-year data from the TROG 03.04 RADAR trial.

Pathology·2021
Same author

Findings in 1,123 Men with Preoperative <sup>68</sup>Ga-Prostate-Specific Membrane Antigen Positron Emission Tomography/Computerized Tomography and Multiparametric Magnetic Resonance Imaging Compared to Totally Embedded Radical Prostatectomy Histopathology: Implications for the Diagnosis and Management of Prostate Cancer.

The Journal of urology·2021
Same author

The novel collagen matrikine, endotrophin, is associated with mortality and cardiovascular events in patients with atherosclerosis.

Journal of internal medicine·2021
Same author

Activation of immune responses against the basement membrane component collagen type IV does not affect the development of atherosclerosis in ApoE-deficient mice.

Scientific reports·2019
Same author

A biomarker of collagen type I degradation is associated with cardiovascular events and mortality in patients with atherosclerosis.

Journal of internal medicine·2018
Same journal

Preventing Postpartum Pelvic Floor Dysfunction: Clinical Evidence and Policy Gaps in U.S. Coverage of Pelvic Floor Muscle Therapy.

Urology·2026
Same journal

Editorial Comment on "Through the Eyes of the Applicant: A Qualitative Study of the Urology Residency Match".

Urology·2026
Same journal

Editorial Comment on "A Histopathologic Assessment of Prostate Ductal Anatomy in Relation to Micro-Ultrasound".

Urology·2026
Same journal

Same-Day Discharge Following Multiport Robot-Assisted Simple Prostatectomy: A Prospective Feasibility Study of Outcomes, Costs, and Post-Discharge Healthcare Utilization.

Urology·2026
Same journal

Extended versus Standard Lymph Node Dissection at the Time of Radical Cystectomy for Bladder Cancer.

Urology·2026
Same journal

Intractable Epistaxis and Severe Hypertension in a Young Woman.

Urology·2026
See all related articles

This study used 3D reconstruction to map prostate cancer distribution in 81 prostates. Small prostate cancers were predominantly found in the lower, dorsolateral regions of the gland.

Area of Science:

  • Urological Oncology
  • Medical Imaging
  • Computational Anatomy

Background:

  • Prostate cancer diagnosis relies on understanding tumor location.
  • Accurate mapping of cancer distribution is crucial for treatment planning.

Purpose of the Study:

  • To visualize and analyze the spatial distribution of prostate cancer using computer-assisted 3D reconstruction.
  • To create a generalized model of cancer distribution across different prostate sizes.

Main Methods:

  • Utilized data from 81 surgically removed prostates.
  • Employed 3D reconstruction and morphing techniques to standardize prostate shapes.
  • Overlaid cancer distribution data onto a "unit prostate" model.
  • Analyzed distribution patterns for small, medium, and large volume cancers.

Related Experiment Videos

Main Results:

  • Generated a detailed 3D "scatter diagram" of prostate cancer distribution.
  • Confirmed that small prostate cancers are primarily located in the lower one-third, dorsolateral aspect of the gland.

Conclusions:

  • The findings provide a statistical representation of prostate cancer localization.
  • This research serves as a preliminary step towards optimizing prostate cancer needle biopsy protocols.