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[Plasma homocysteine levels in patients with transient ischemic attacks]
J Alvarez Sabín1, J Turón, J Montaner
1Unidad Cerebrovascular, Hospital General Universitario Vall d'Hebron, Barcelona.
Medicina Clinica
|December 22, 1999
Abstract
Objective:
To evaluate plasma homocysteine (Hcy) levels in patients with atherotrombotic transient ischemic attacks (TIA), its temporal profile and response to folic acid (FA) treatment.
Patients And Methods:
Hcy was determined in 62 patients and in 69 controls.
Results:
There were no differences (p < 0.87) of baseline Hcy in TIA patients vs controls. Hcy levels were higher 4-6 weeks after TIA (p = 0.02). FA treatment decreases the Hcy levels (p < 0.00001).
Conclusion:
Hyperhomocisteinemia is a possible risk factor for atherothrombotic TIA and should be measured between 4-6 weeks after TIA. Treatment with FA normalizes Hcy levels.