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Generalised granuloma annulare successfully treated with PUVA
J Setterfield1, S C Huilgol, M M Black
1St John's Institute of Dermatology, St Thomas' Hospital, London. j.setterfield@umds.ac.uk
Clinical and Experimental Dermatology
|December 22, 1999
Summary
Disseminated granuloma annulare (DGA) treatment can be challenging. This study shows successful long-term remission of DGA using 5-methoxypsoralen photochemotherapy.
Area of Science:
- Dermatology
- Photomedicine
Background:
- Disseminated granuloma annulare (DGA) is a rare dermatosis with limited treatment options.
- Topical and systemic therapies often yield suboptimal results for DGA.
Observation:
- A single patient with disseminated granuloma annulare was treated with 5-methoxypsoralen photochemotherapy.
- Treatment duration was seven months.
Findings:
- The patient achieved complete disease clearance.
- Remission was maintained for a 20-month follow-up period without requiring maintenance therapy.
Implications:
- 5-methoxypsoralen photochemotherapy may offer a viable, potentially curative, treatment for disseminated granuloma annulare.
- This approach could eliminate the need for long-term maintenance therapy often associated with PUVA treatments.