Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Bone Disorders01:29

Bone Disorders

Aging and its effect on bone remodeling is the most common cause of bone disorders. In young and healthy people, bone deposition and resorption happen at an equal rate to maintain optimal bone health.
Bone deposition is also affected by the levels of sex hormones like estrogen and testosterone that promote osteoblast activity and bone matrix synthesis. When the level of these hormones decreases due to aging, it causes a reduction in bone deposition. As a result, bone resorption by osteoclasts...
Documentation in Long-Term and Home Healthcare Setting01:29

Documentation in Long-Term and Home Healthcare Setting

Documentation in long-term care facilities and home healthcare settings is crucial for ensuring continuous, coordinated, and comprehensive care for patients. Each setting has its specific documentation processes and tools:
Long-Term Care Facilities
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution01:00

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Distribution

Drug distribution in the human body is influenced by several factors, including plasma protein concentration, body composition, blood flow, tissue-protein concentration, and tissue fluid pH. Among these, changes in plasma protein concentration and body composition due to aging significantly affect how drugs are distributed within the body. Specifically, aging is associated with a decrease in albumin levels by about 10% and an increase in α1-acid glycoprotein levels. These alterations are not...
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Metabolism

Geriatric patients show significant variation in how their bodies process medications, which can change how effective and safe treatments are. The liver is the primary organ where drug metabolism occurs, involving two main types of chemical reactions: phase I and II. Phase I metabolism is driven by the cytochrome P450 enzyme system, which includes key types such as CYP3A, CYP2D6, and CYP2C9. Research indicates that while aging doesn't notably alter the levels or activity of these enzymes, it...
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The feasibility of K XRF bone lead measurements in mice assessed using 3D-printed phantoms.

Biomedical physics & engineering express·2024
Same author

Adjustable coupling and in situ variable frequency electron paramagnetic resonance probe with loop-gap resonators for spectroscopy up to X-band.

The Review of scientific instruments·2020
Same author

Erratum to: identifying consumer's needs of health information technology through an innovative participatory design approach among English- and Spanish-speaking urban older adults.

Applied clinical informatics·2015
Same author

Identifying consumer's needs of health information technology through an innovative participatory design approach among English- and Spanish-speaking urban older adults.

Applied clinical informatics·2015
Same author

Developing clinical decision support within a commercial electronic health record system to improve antimicrobial prescribing in the neonatal ICU.

Applied clinical informatics·2014
Same author

Exercise for depression in care home residents: a randomised controlled trial with cost-effectiveness analysis (OPERA).

Health technology assessment (Winchester, England)·2013
Same journal

Central Nervous System (CNS) Medication Use Before Suicide Among Older Adults in Sweden From 2007 to 2020: A Register-Based Case-Control Study.

International journal of geriatric psychiatry·2026
Same journal

Older Patients With Memory Complaints Often Prefer Diagnostics in Primary Care or No Further Diagnostic Evaluation.

International journal of geriatric psychiatry·2026
Same journal

Long-Term Perceptions of the Value of Amyloid PET Scans Among Cognitively Impaired Medicare Beneficiaries and Their Care Partners.

International journal of geriatric psychiatry·2026
Same journal

Assessing the Utility of Automated and Pen-And-Paper Cognitive Assessment Tools for Underrepresented Groups in the UK.

International journal of geriatric psychiatry·2026
Same journal

Resource Use in Swedish Nursing Homes: A Repeated Cross-Sectional Follow-Up Study.

International journal of geriatric psychiatry·2026
Same journal

Health Inequalities Within Dementia Care Pathways.

International journal of geriatric psychiatry·2026
See all related articles

Related Experiment Video

Updated: Jun 22, 2026

Oral Health Assessment by Lay Personnel for Older Adults
08:47

Oral Health Assessment by Lay Personnel for Older Adults

Published on: February 2, 2020

Review: Somatization in the elderly.

B Sheehan1, S Banerjee

  • 1Maudsley Hospital, Denmark Hill, London, UK.

International Journal of Geriatric Psychiatry
|December 23, 1999
PubMed
Summary
This summary is machine-generated.

Somatization, the experience of distress as physical symptoms, is common in elderly patients and often linked to depression and other psychiatric conditions. Effective treatment requires addressing these underlying psychological factors.

More Related Videos

Validation of a Psychosocial Intervention on Body Image in Older People: An Experimental Design
07:40

Validation of a Psychosocial Intervention on Body Image in Older People: An Experimental Design

Published on: May 31, 2021

Therapeutic Massage for Psychological Well-being in Geriatric Oncology
03:59

Therapeutic Massage for Psychological Well-being in Geriatric Oncology

Published on: May 22, 2026

Related Experiment Videos

Last Updated: Jun 22, 2026

Oral Health Assessment by Lay Personnel for Older Adults
08:47

Oral Health Assessment by Lay Personnel for Older Adults

Published on: February 2, 2020

Validation of a Psychosocial Intervention on Body Image in Older People: An Experimental Design
07:40

Validation of a Psychosocial Intervention on Body Image in Older People: An Experimental Design

Published on: May 31, 2021

Therapeutic Massage for Psychological Well-being in Geriatric Oncology
03:59

Therapeutic Massage for Psychological Well-being in Geriatric Oncology

Published on: May 22, 2026

Area of Science:

  • Geriatric Medicine
  • Psychiatry
  • Clinical Psychology

Background:

  • Somatization is a prevalent medical issue, often linked to increased healthcare utilization and treatment challenges.
  • In the elderly, somatization has been historically viewed as a manifestation of depression, though research shows mixed results regarding increased prevalence.
  • Elderly individuals may underreport physical symptoms, complicating the assessment of somatization.

Purpose of the Study:

  • To explore the presentation and potential etiological factors of somatization in the elderly population.
  • To examine the relationship between somatization, depression, and physical illness in older adults.
  • To identify key factors influencing somatization in the elderly and inform treatment approaches.

Main Methods:

  • Review of existing literature on somatization in the elderly.
  • Analysis of population studies examining somatization trends in older adults.
  • Exploration of the association between somatization, depression, physical illness, and psychological distress in the elderly.

Main Results:

  • Somatization is common in elderly patients, particularly those who are depressed.
  • The presence of co-occurring physical illness may increase somatization in depressed elderly individuals.
  • Psychological distress is typically acknowledged rather than masked in elderly patients with depression.
  • Neuroticism and other psychiatric illnesses are identified as potential etiological factors for somatization in the elderly.

Conclusions:

  • Somatization in the elderly is complex and associated with underlying psychiatric disorders, not solely masked depression.
  • Treatment strategies should incorporate management of co-existing psychiatric conditions.
  • Further research is needed to develop and evaluate specific treatments for somatization in the elderly.