Red blood cells, hemoglobin and the immune system

The paramount function of the red blood cells (RBCs) is generally reckoned to be oxygen carriage. The possibility that they now participate in the defensive mechanism of the human body is ignored and neglected, despite the fact that the RBCs are both mechanical and biochemical barriers against infections, bacteria, and blood parasites. Immune reactions are regulated to ensure harmony between the red and white blood cell populations. This hypothesis will lead to better comprehension of blood cell functions in various physiological and pathological conditions.