Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Recent developments in SWL physics research.

P Zhong1, X Xi, S Zhu

  • 1Department of Mechanical Engineering and Materials Science, Duke University, Durham, North Carolina 27708-0300, USA. pz1@me1.egr.duke.edu

Journal of Endourology
|December 23, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

[Development and validation of a risk prediction model for early postoperative high intraocular pressure after implantation of posterior chamber intraocular lens].

Zhonghua yi xue za zhi·2025
Same author

[Analysis of the influencing factors of short-term and long-term facial nerve function after vestibular schwannoma resection via suboccipital retrosigmoid approach].

Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery·2024
Same author

[Characteristics of autonomic neuropathy in patients with vestibular migraine].

Zhonghua yi xue za zhi·2023
Same author

[A case report of neck congenital fibrosarcoma in newborns].

Zhonghua er bi yan hou tou jing wai ke za zhi = Chinese journal of otorhinolaryngology head and neck surgery·2022
Same author

Anti-Inflammatory and Anti-Oxidant Activity of Ultra-Short Wave Diathermy on LPS-Induced Rat Lung Injury.

Bulletin of experimental biology and medicine·2022
Same author

Correction: Elevation of p11 in lateral habenula mediates depression-like behavior.

Molecular psychiatry·2019
Same journal

Is Nonpapillary Puncture a Feasible Alternative to Papillary Access in Percutaneous Nephrolithotomy? A Systematic Review and Meta-Analysis.

Journal of endourology·2026
Same journal

Procedure, Safety, and Outcomes of Patient-Controlled Sedation in Ureteroscopic Lithotripsy: A 7-Year Cohort Study.

Journal of endourology·2026
Same journal

Clinically Significant Prostate Cancer in Patients Undergoing Holmium Laser Enucleation of Prostate for Benign Hyperplasia: A Preoperative Nomogram and a Postoperative Surveillance Protocol.

Journal of endourology·2026
Same journal

Bubble Trouble: The Thermal Risk of Ureteral Laser Lithotripsy in an Air Bubble.

Journal of endourology·2026
Same journal

Development of an Interpretable Machine Learning Model for Predicting Clavien-Dindo Grade ≥2 Complications after Unilateral Minimally Invasive Pyeloplasty in UPJO: A Retrospective Cohort Study.

Journal of endourology·2026
Same journal

Comparison of Appendiceal Onlay Ureteroplasty and Appendiceal Interposition Ureteroplasty for Complex Proximal Ureteral Strictures in Children: Insights Gained from Long-Term Follow-Up.

Journal of endourology·2026
See all related articles

Researchers improved shockwave lithotripsy (SWL) by controlling cavitation bubbles with a piezoelectric annular array (PEAA) generator. This enhanced stone fragmentation. SWL-induced cavitation in vivo is constrained by tissue, potentially causing vessel rupture.

Area of Science:

  • Biomedical Engineering
  • Medical Physics
  • Acoustic Cavitation

Background:

  • Shockwave lithotripsy (SWL) is a common procedure for kidney stone removal.
  • Cavitation bubble dynamics significantly impact SWL efficacy and safety.
  • Controlling cavitation is crucial for optimizing SWL treatment.

Purpose of the Study:

  • To investigate methods for active control of cavitation during SWL.
  • To analyze the impact of constrained bubble dynamics on SWL outcomes.
  • To experimentally validate the influence of tissue confinement on SWL-induced cavitation.

Main Methods:

  • Development of a prototype piezoelectric annular array (PEAA) shockwave generator for retrofitting on existing lithotripters.
  • Utilizing high-speed shadowgraph imaging to visualize bubble dynamics in vascular phantoms.

Related Experiment Videos

  • In vitro stone fragmentation experiments using controlled cavitation bubble collapse.

    • Main Results:

    • The PEAA generator successfully controlled cavitation bubble collapse, significantly improving in vitro stone fragmentation.
    • Cavitation bubble expansion was significantly constrained in silicone tubes and hollow fibers compared to free oscillation.
    • Rupture of cellulose hollow fibers was observed, indicating potential for vessel damage from constrained SWL cavitation.

    Conclusions:

    • Active control of cavitation using PEAA technology can enhance SWL stone fragmentation.
    • Tissue confinement significantly constrains SWL-induced cavitation bubble dynamics in vivo.
    • Large intraluminal bubble expansions due to constrained cavitation may lead to vascular rupture.