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[Biological monitoring of liver transplantation]
1Service de Chirurgie Digestive, Hôpital Cochin, Paris, France.
Abstract:
Liver transplantation is now a widely used therapeutic option that has been proved effective, although the inadequate supply of transplants remains a problem. Laboratory tests are important at three different periods in time: prior to transplantation to aid in patient selection and to look for contra-indications to transplantation; during the transplant procedure to ensure real-time evaluation of vital metabolic parameters; and, above all, after the procedure to assist in the detection of complications. These can occur early (preservation lesions, acute rejection, side effects of immuno-suppressive agents, infections, renal failure, etc.), as a direct result of the surgical procedure (blood vessel or bile duct injury), or late (chronic rejection, recurrence of the initial disease, treatment-induced cancer).