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Medicinal herbs: drugs or dietary supplements?
1Pharmanex, Inc., Brisbane, CA 94005, USA. jchang@pharmanex.com
Biochemical Pharmacology
|December 28, 1999
Summary
Evaluating medicinal herbs requires a defined strategy for safe and effective products. Standardized herbal extracts offer consistent pharmacological activity, but their complex composition must be understood for drug development.
Area of Science:
- Pharmacology
- Phytochemistry
- Drug Development
Background:
- Evaluating medicinal herbs for safety and efficacy presents complex challenges.
- Standardized herbal extracts offer a viable approach to consistent pharmacological activity.
- The pharmacological effects of isolated compounds can differ from the whole herb.
Purpose of the Study:
- To discuss a research-based strategy for validating the health benefits of medicinal herbs.
- To review the scientific evidence supporting the pharmacological activity of various herbs.
Main Methods:
- Literature review of scientific evidence on herbal pharmacological activity.
- Discussion of research strategies for validating herbal product efficacy.
- Analysis of the complexities in developing standardized herbal extracts.
Main Results:
- Herbal extracts can exhibit different pharmacological effects compared to the whole herb.
- Standardized extracts require understanding of multiple active ingredients for consistent action.
- Evidence supports the pharmacological activity of several medicinal herbs.
Conclusions:
- A robust research strategy is crucial for developing safe and effective herbal products.
- Further research is needed to fully understand the pharmacological actions of herbal extracts.
- Standardized herbal extracts represent a promising avenue for drug development.