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Updated: Jul 30, 2026
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A New Murine Model of Endovascular Aortic Aneurysm Repair
Published on: July 7, 2013
A fenestrated covered suprarenal aortic stent
T F Browne1, D Hartley, S Purchas
1Department of Surgery, Broomfield Hospital, Chelmsford, Essex, UK.
Summary
A novel fenestrated stent design addresses challenges in endovascular aneurysm repair by preserving renal artery blood flow. This innovation may expand treatment options for abdominal aortic aneurysms.
Area of Science:
- Vascular Surgery
- Biomedical Engineering
- Medical Device Design
Background:
- Abdominal aortic aneurysms (AAAs) pose a significant clinical challenge, particularly when inadequate neck length complicates endovascular repair.
- Current endovascular techniques may be limited by the anatomy of the aneurysm neck, restricting treatment options.
Purpose of the Study:
- To develop and evaluate a novel stent design for endovascular repair of AAAs with challenging neck lengths.
- To address the limitation of inadequate infrarenal neck length in abdominal aortic aneurysms for endovascular grafting.
Main Methods:
- A suprarenal stent was designed with a fenestration to maintain flow to a specific renal artery.
- The Dacron-covered stent was custom-sized using pre-procedural imaging and featured a precise fenestration.
Main Results:
- Successful deployment of the fenestrated stent was achieved in canine models.
- The stent design effectively preserved blood flow to the targeted renal artery and associated visceral branches.
Conclusions:
- Accurate placement of fenestrated, covered aortic stents can preserve vital branch artery flow.
- This approach holds potential for expanding the indications for endovascular aortic aneurysm repair, offering a solution for complex anatomies.
