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Updated: Aug 8, 2026

Tilt Testing with Combined Lower Body Negative Pressure: a "Gold Standard" for Measuring Orthostatic Tolerance
Published on: March 21, 2013
[Gestosis: predictive value of clinoorthostatic test with ECG]
Aim:
To examine value of the clinoorthostatic test (COT) with ECG conducted in pregnancy trimesters I, II and III for prediction of gestosis.
Materials And Methods:
The trial included 66 healthy gravidae aged 18-26 years (mean age 19.1 +/- 2.84 years) and 135 gravidae with extragenital pathology aged 17-43 years (mean age 25.1 +/- 0.78 years) on pregnancy trimester I, II and III. Within the observation period the gravidae underwent 3-4 COT with ECG. Arterial pressure and ECG were registered in dorsal and erect positions on minute 1, 3 and 10 on pregnancy week 9-12, 16-18, 26-28.
Results:
Most of the gravidae who subsequently developed gestosis on trimester I exhibited cardiovascular maladaptation recordable at COT with ECG. Comparison of COT results with pregnancy outcomes gave grounds for establishment of 12 prognostic tests predicting gestosis with probability 75-100% in the tests sensitivity at least 80%, specificity 89%.
Conclusion:
COT with ECG is a simple, available and informative method of predicting gestosis and can be used by obstetricians for detection of gestosis risk groups among the gravidae.
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