Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Central mutation databases--a review.

C J Porter1, C C Talbot, A J Cuticchia

  • 1Johns Hopkins University, Baltimore, Maryland, USA.

Human Mutation
|December 29, 1999
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Transcriptome analysis of blastoderms exposed to prolonged egg storage and short periods of incubation during egg storage.

BMC genomics·2022
Same author

MicroRNA-132 dysregulation in Toxoplasma gondii infection has implications for dopamine signaling pathway.

Neuroscience·2014
Same author

Multilocus sequence typing of human and canine C. upsaliensis isolates.

Veterinary microbiology·2012
Same author

Risk factors for the carriage of Campylobacter upsaliensis by dogs in a community in Cheshire.

The Veterinary record·2009
Same author

Typing of Campylobacter jejuni isolates from dogs by use of multilocus sequence typing and pulsed-field gel electrophoresis.

Journal of clinical microbiology·2009
Same author

Prevalence of Campylobacter spp. in a cross-sectional study of dogs attending veterinary practices in the UK and risk indicators associated with shedding.

Veterinary journal (London, England : 1997)·2009
Same journal

RETRACTION: "Differential Effects of AKT1(p.E17K) Expression on Human Mammary Luminal Epithelial and Myoepithelial Cells".

Human mutation·2026
Same journal

Diagnostic Yield of Genome Sequencing in an Iranian Exome-Negative Autosomal-Recessive Intellectual Disability Cohort.

Human mutation·2026
Same journal

Exploring the Functional Impact of Individual <i>DDX41</i> Variants With a Fast and Robust Cell-Based Method.

Human mutation·2026
Same journal

Modeling the Effects of Single Nucleotide Polymorphisms (SNPs) on the Structure and Function of the Human <i>RET</i> Gene: An In Silico Study.

Human mutation·2026
Same journal

Driver Mutation Subtypes Differentially Shape Immune Evasion Landscapes in Melanoma: An AI-Driven Inflammatory Pathway Model Implicating CCNE1.

Human mutation·2026
Same journal

Comment on "When the Outcome Contains the Exposure: Methodological Limits of a Genome-Wide Cross-Trait Analysis of Type 2 Diabetes and MASLD".

Human mutation·2026
See all related articles

The Internet facilitated the Human Genome Project by enabling global data sharing. Central databases use the internet to aggregate genetic variation data from worldwide researchers for the human genomics community.

Area of Science:

  • Genomics
  • Bioinformatics
  • Internet Technologies

Background:

  • The Human Genome Project involved a large, geographically dispersed team of scientists.
  • Effective coordination and data exchange were crucial for project success.
  • Managing and sharing information on genetic variation and mutation presented significant challenges.

Purpose of the Study:

  • To highlight the critical role of the Internet in coordinating the Human Genome Project.
  • To emphasize the importance of internet-based data exchange for genetic variation information.
  • To describe the function of central databases in assembling and disseminating genomic data.

Main Methods:

  • Utilizing the Internet for communication and data transfer among research sites.
  • Establishing central databases to collect and store genetic variation data.

Related Experiment Videos

  • Developing protocols for accessing and sharing information with the wider scientific community.

    • Main Results:

    • The Internet enabled seamless coordination among diverse scientific groups.
    • Efficient maintenance and exchange of genetic variation and mutation data were achieved.
    • Central databases successfully aggregated data from numerous global research sites.

    Conclusions:

    • The Internet was indispensable for the Human Genome Project's collaborative nature.
    • Internet-enabled data sharing is vital for advancing human genomics research.
    • Centralized data repositories are essential for making global genomic discoveries accessible.