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[Normal values for transcranial doppler studies in our medium].

T Segura1, J Serena, I Plaza

  • 1Sección de Neurología, Hospital Josep Trueta, Girona. tseguram@nexo.es

Neurologia (Barcelona, Spain)
|December 29, 1999
PubMed
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Establishing reference values for transcranial Doppler (TCD) in Spain is crucial. This study determined mean velocity and pulsatility index in a healthy population, finding significant differences based on age and sex.

Area of Science:

  • Neuroscience
  • Vascular Biology
  • Medical Imaging

Background:

  • Transcranial Doppler (TCD) is increasingly utilized for intracranial artery assessment and cerebrovascular disease diagnosis.
  • Typical TCD values for a healthy Spanish population are currently undefined.
  • This study addresses the need for establishing normative TCD data within this demographic.

Purpose of the Study:

  • To determine reference values for mean velocity and pulsatility index in the intracranial arteries of a healthy Spanish population.
  • To provide a baseline for TCD interpretation in clinical practice.
  • To investigate potential variations in TCD parameters based on demographic factors.

Main Methods:

  • A basal transcranial Doppler examination was performed on 118 healthy volunteers.

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  • Exclusion criteria included prior hematological/cerebrovascular conditions and inability to insonate middle cerebral arteries due to temporal bone hyperostosis.
  • Mean and standard deviations of TCD variables were calculated for different age groups and sexes.
  • Main Results:

    • A usable signal for TCD parameter assessment was obtained in 89% of middle cerebral arteries.
    • Statistically significant differences in mean velocity and pulsatility index were observed between various age groups.
    • Significant variations in mean velocity and pulsatility index were also found between sexes.

    Conclusions:

    • Age and sex are critical factors influencing typical transcranial Doppler patterns.
    • The study establishes reference parameters for mean velocity and pulsatility index in the adult Spanish population.
    • These findings are essential for accurate TCD interpretation and diagnosis of cerebrovascular conditions in Spain.