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Updated: Oct 3, 2026

Characterization of the Isolated, Ventilated, and Instrumented Mouse Lung Perfused with Pulsatile Flow
Published on: April 29, 2011
[Course of pulmonary hemodynamics in intermittent ventilation]
F Herth1, M R Schulz, V Schulz
1Thoraxklinik, Abteilung Pneumonologie Heidelberg.
Abstract:
Patients with chronic respiratory failure often show an elevated pulmonary vascular resistance. We examined in a prospective study with the follow-up of patients with intermittent non-invasive ventilation (nISB) and pulmonary hypertension using dobutamine stress echocardiography. The data show that ISB lowers the pressure in all patients, more in patients with restrictive diseases, due to thoracic deformities, than in patients with COPD.
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