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Updated: Jul 31, 2026
06:45
Colon Ascendens Stent Peritonitis (CASP) - a Standardized Model for Polymicrobial Abdominal Sepsis
Published on: December 18, 2010
Seprafilm-induced peritoneal inflammation: a previously unknown complication. Report of a case
P J Klingler1, N R Floch, M H Seelig
1Department of General Surgery, Mayo Clinic Jacksonville, Florida 32224, USA.
Diseases of the Colon and Rectum
|December 29, 1999
Summary
Bioresorbable membranes, used to prevent postoperative adhesions, can cause severe inflammatory reactions. While generally safe, surgeons should be aware of this potential complication.
Area of Science:
- Adhesion prevention
- Surgical complications
- Biomaterials
Background:
- Postoperative adhesions are a common surgical complication.
- Sodium hyaluronate-based bioresorbable membranes are increasingly used for adhesion prevention.
- Previous studies suggested these membranes are safe and effective.
Observation:
- This report details the first case of a severe inflammatory reaction to a bioresorbable membrane.
- A literature review was conducted to identify similar cases and understand the risks.
Findings:
- Bioresorbable membranes, despite promising results, can elicit significant inflammatory responses.
- The incidence and severity of these reactions require further investigation.
Implications:
- General surgeons and gynecologists should be aware of the potential for severe inflammatory reactions.
- Careful patient selection and monitoring may be necessary when using these devices.
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