Related Experiment Video
Updated: Jul 31, 2026

Colon Ascendens Stent Peritonitis (CASP) - a Standardized Model for Polymicrobial Abdominal Sepsis
Published on: December 18, 2010
Seprafilm-induced peritoneal inflammation: a previously unknown complication. Report of a case
P J Klingler1, N R Floch, M H Seelig
1Department of General Surgery, Mayo Clinic Jacksonville, Florida 32224, USA.
Introduction:
Various substances and agents have been evaluated to prevent postoperative adhesion formation. Recently a sodium hyaluronate-based bioresorbable membrane was introduced with promising clinical results. Its application was regarded as safe and efficient.
Methods:
We present the first reported case of a severe inflammatory reaction to a bioresorbable membrane and give a review of the related literature.
Conclusion:
Bioresorbable membranes are increasingly used by general surgeons and gynecologists to reduce postoperative adhesion formation. Bioresorbable membranes may produce extensive inflammatory reactions.
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