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Mortality among aircraft manufacturing workers.

J D Boice¹, D E Marano, J P Fryzek

¹International Epidemiology Institute, Rockville, MD 20850-3127, USA.

Occupational and Environmental Medicine

|January 1, 2000

Summary

This study found no clear evidence of increased cancer or disease risk in aircraft manufacturing workers exposed to chromate, trichloroethylene (TCE), perchloroethylene (PCE), or mixed solvents. Overall mortality and cancer rates were at or below expected levels for the general population.

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Area of Science:

Occupational Health
Environmental Epidemiology
Toxicology

Background:

Aircraft manufacturing involves potential exposure to hazardous chemicals like chromates and solvents.
Previous studies on aircraft workers have yielded varied results regarding cancer risks.

Purpose of the Study:

To assess cancer and other disease risks in aircraft manufacturing workers.
To evaluate the impact of specific chemical exposures including chromate, trichloroethylene (TCE), perchloroethylene (PCE), and mixed solvents.

Main Methods:

A retrospective cohort mortality study of 77,965 aircraft workers from 1960 to 1996.
Standardized Mortality Ratios (SMRs) compared observed deaths to expected general population rates.
Poisson regression analyses assessed risks associated with specific chemical exposures and duration.

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Main Results:

Overall mortality (SMR 0.83) and cancer mortality (SMR 0.90) were low.
No significant increases in risk for any of the 40 specific causes of death were observed.
Workers exposed to chromate, TCE, PCE, or mixed solvents did not show increased total or lung cancer risk.

Conclusions:

This large-scale, long-term study provides no clear evidence of elevated cancer or disease risk from occupational exposures in aircraft manufacturing.
Findings align with prior research indicating generally expected or lower cancer risks in this industry.