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Related Experiment Video

Updated: Jul 20, 2026

Scleral Cross-linking Using Riboflavin and Ultraviolet-A Radiation for Prevention of Axial Myopia in a Rabbit Model

Scleral Cross-linking Using Riboflavin and Ultraviolet-A Radiation for Prevention of Axial Myopia in a Rabbit Model

Published on: April 3, 2016

Oculomotor functions and late-onset myopia.

B C Jiang¹, S E Morse

¹College of Optometry, University of Houston, TX 77204-6052, USA.

Ophthalmic & Physiological Optics : the Journal of the British College of Ophthalmic Opticians (Optometrists)

|January 1, 2000

Summary

Individuals prone to late-onset myopia (LOM) may have a distinct oculomotor risk profile, characterized by a higher threshold to optical defocus signals. This suggests a potential mechanism for myopia development linked to sustained near-work.

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Binocular Dynamic Visual Acuity in Eyeglass-Corrected Myopic Patients

Binocular Dynamic Visual Acuity in Eyeglass-Corrected Myopic Patients

Published on: March 29, 2022

Area of Science:

Ophthalmology
Vision Science
Biophysics

Background:

Late-onset myopia (LOM) development is influenced by optical defocus.
Previous theoretical models suggested sensory components may alter the accommodative system's response to defocus.

Purpose of the Study:

To investigate the role of optical defocus in LOM development.
To compare perceptual depth-of-focus and defocus thresholds across different refractive error groups.

Main Methods:

Theoretical modeling of the accommodation system with an added sensory operator.
Experimental measurement of perceptual depth-of-focus.
Measurement of the accommodative system's threshold to defocus signals in emmetropic, stable myopic, and progressing myopic individuals.

Main Results:

No significant differences in perceptual depth-of-focus were found among the three refractive error groups.
Progressing myopic individuals exhibited significantly higher defocus threshold values compared to emmetropic and stable myopic individuals.

Conclusions:

Individuals susceptible to myopia from sustained near-work may possess a specific oculomotor risk profile.
Changes in oculomotor parameters, including defocus threshold, are implicated in the development of myopia associated with near-work.