Related Experiment Video
Updated: Aug 15, 2026

Design of a Cyclic Pressure Bioreactor for the Ex Vivo Study of Aortic Heart Valves
Published on: August 23, 2011
[Safety of oxygen-pressure-reducing valves]
1Service de pharmacie, hôpital Laennec, Paris, France.
Abstract:
When a gas cylinder valve is opened slowly, as required, the associated pressure reducing valve works properly and gas expansion decreases the temperature of the device proportionally to the delivered gas flow. Conversely, when the valve is opened rapidly, the pressure in the high pressure chamber grows suddenly from 0 to 200 bars in the case of a full O2-cylinder, if no flow is required at the valve outlet. This adiabatic compression in a small space generates a peak of high temperature. In the presence of combustible foreign debris and O2, ignition can occur. When the melting point of the metallic component is reached the device bursts and those in the vicinity are at risk of burns or death from inhalation of melten metallic debris. As several of such critical incidents occurred with O2-pressure-reducing valves whose high pressure chambers were made of aluminium, the French medical devices agency has enacted a regulation prohibiting their use.
Related Concept Videos
Treatment for Pulmonary Arterial Hypertension: Oxygen Therapy for Respiratory Failure
Oxygen therapy is vital in increasing and maintaining blood oxygen levels in PAH patients. As a result, it aids in reducing fatigue, improving...
Oxygen Delivering System I: Nasal Cannula and Face Mask
Nasal Cannula
A nasal cannula is a lightweight tube split at one end into two prongs and placed in the nostrils. It is typically used to deliver low to medium levels of oxygen.
Suggested flow rate: The suggested flow rate for a nasal cannula typically ranges between 1 and 6 L/min.
Oxygen percentage setting:...
Oxygen Delivering System II: Venturi Mask and Transtracheal Oxygen
Venturi Mask
The Venturi mask, named after the Venturi effect, is designed to deliver precise oxygen concentrations. It consists of a large tube with an oxygen inlet that narrows down, causing a pressure drop that pulls air in through adjustable side ports. The mask is a lightweight,...
Oxygen Delivering System III: Tracheostomy and T-piece
Tracheostomy
A tracheostomy is a surgically created opening (stoma) in the anterior part of the trachea. It is used to establish a patient airway, bypass an upper airway obstruction, simplify the removal of secretions, permit long-term...
Administering Oxygen by Mask
Administering oxygen by mask is a common nursing intervention that provides supplemental oxygen to patients with respiratory distress or chronic lung conditions. This procedure involves delivering oxygen at a specified rate through a face mask connected to an oxygen source.
Equipment
The equipment necessary for this procedure includes:
Oxygen Requirements and Growth Patterns

