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Post-coital antifertility activity of Acalypha indica L
S P Hiremath1, K Rudresh, S Badami
1Department of Chemistry, Gulbarga University, India.
Journal of Ethnopharmacology
|January 5, 2000
Abstract:
Four successive solvent extracts of the whole plant Acalypha indica L. (Euphorbiaceae) were tested for post-coital antifertility activity in female albino rats. Of these, the petroleum ether and ethanol extracts were found to be most effective in causing significant anti-implantation activity. The antifertility activity was reversible on withdrawal of the treatment of the extracts. Both the extracts at 600 mg/kg body weight showed estrogenic activity. Histological studies of the uterus were carried out to confirm this estrogenic activity.