Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Colophony allergy: a review.

A M Downs1, J E Sansom

  • 1Department of Dermatology, Bristol Royal Infirmary, UK.

Contact Dermatitis
|January 5, 2000
PubMed
Summary

Colophony allergy is common due to oxidation products. Standard screening may miss allergies to modified colophony, necessitating broader testing for accurate diagnosis.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Tunable stiffness enables fast and efficient swimming in fish-like robots.

Science robotics·2021
Same author

Occupational dermatoses during the COVID-19 pandemic: a multicentre audit in the UK and Ireland.

The British journal of dermatology·2020
Same author

A service evaluation between 2-week wait (2WW) skin cancer referrals via teledermatology and the standard face-to-face pathway at a teaching hospital.

Clinical and experimental dermatology·2019
Same author

Localization of α7 nicotinic acetylcholine receptor mRNA and protein within the cholinergic anti-inflammatory pathway.

Neuroscience·2014
Same author

Practical experience of ustekinumab in the treatment of psoriasis: experience from a multicentre, retrospective case cohort study across the U.K. and Ireland.

The British journal of dermatology·2011
Same author

Allergic contact dermatitis from bisphenol-A-glycidyldimethacrylate during application of orthodontic fixed appliance.

Contact dermatitis·2006

Area of Science:

  • Allergen immunotherapy
  • Contact dermatitis

Background:

  • Colophony, derived from pine trees, is a complex mixture with widespread industrial and domestic applications.
  • Exposure to colophony and its modified forms is ubiquitous, leading to potential allergic reactions.
  • Oxidation products of colophony and novel resin acids from modification are identified as primary allergens.

Purpose of the Study:

  • To investigate the allergens responsible for colophony allergy.
  • To evaluate the effectiveness of standard screening methods for colophony allergy.
  • To determine if current screening protocols adequately identify allergies to modified colophony.

Main Methods:

  • Analysis of colophony composition, including oxidation products and resin acids.
  • Evaluation of patient reactions to both unmodified and modified colophony.
  • Comparison of screening results using different colophony preparations (e.g., gum rosin, 20% pet).

Main Results:

  • Oxidation products and specific resin acids are the principal allergens in colophony.
  • Standard screening with unmodified gum rosin may fail to detect allergies to modified colophony.
  • A significant portion of positive reactions may be attributed to unmodified colophony present in both tested materials, rather than cross-reactivity.

Conclusions:

  • Current screening methods relying solely on unmodified colophony may miss crucial diagnoses of modified colophony allergy.
  • Comprehensive allergy testing is essential to identify all relevant colophony allergens.
  • Understanding the specific allergenic components is key to improving diagnostic accuracy for colophony hypersensitivity.

Related Experiment Videos