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Updated: Aug 1, 2026
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Isolation of Fidelity Variants of RNA Viruses and Characterization of Virus Mutation Frequency
Published on: June 16, 2011
Establishment of a persistent mutant of canine distemper virus
K Iwatsuki1, Y Ikeda, K Ohashi
1Department of Veterinary Microbiology, Graduate School of Agricultural and Science, The University of Tokyo, 1-1-1 Yayoi, Bunkyo-ku, Tokyo 113-8657, Japan.
Microbes and Infection
|January 5, 2000
Abstract:
We produced a B95a lymphoid cell line persistently infected with canine distemper virus (CDV), in which virus-specific antigens were present in nearly 100% of cells without causing cytopathic effect. The virus recovered from this cell line was able to infect fresh B95a cells persistently, indicating that a persistent CDV was established.
