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Related Experiment Video

Updated: Jun 9, 2026

Perceptual and Category Processing of the Uncanny Valley Hypothesis' Dimension of Human Likeness: Some Methodological Issues
07:34

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Published on: June 3, 2013

Feeling unreal: cognitive processes in depersonalization.

O Guralnik1, J Schmeidler, D Simeon

  • 1Department of Psychiatry, Mount Sinai School of Medicine, New York, NY 10029, USA. 102504.2330@compuserve.com

The American Journal of Psychiatry
|January 5, 2000
PubMed
Summary

Individuals with depersonalization disorder exhibit cognitive deficits in attention and memory. This study reveals specific impairments in processing new information, impacting daily functioning.

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Area of Science:

  • Neuroscience
  • Psychiatry
  • Cognitive Psychology

Background:

  • Depersonalization disorder involves detachment from self and surroundings, causing distress.
  • Despite reality testing remaining intact, cognitive difficulties are frequently reported.

Purpose of the Study:

  • To investigate the cognitive profiles of individuals with depersonalization disorder.
  • To identify specific neuropsychological deficits associated with the condition.

Main Methods:

  • A comprehensive neuropsychological test battery was administered.
  • Fifteen patients with depersonalization disorder were compared to 15 matched healthy controls.

Main Results:

  • Depersonalization disorder patients showed significant deficits in attention and spatial reasoning.
  • Impaired short-term visual and verbal memory was observed in patients.
  • Overall intellectual abilities were comparable between patients and controls.

Conclusions:

  • Depersonalization may involve alterations in attentional control and perceptual systems.
  • Early encoding deficits in attention are hypothesized to impact short-term memory.
  • Deficits manifest in acquiring new information, not in manipulating existing knowledge.