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Updated: Oct 18, 2026

Constructing Mutants in Serotype 1 Streptococcus pneumoniae strain 519/43
Published on: September 11, 2020
Bacteremic pneumonia caused by a single clone of Streptococcus pneumoniae with different optochin susceptibilities
H Y Tsai1, P R Hsueh, L J Teng
1Department of Pediatrics, Taipei Municipal Ho-Ping Hospital, Taipei, Taiwan.
Abstract:
Two isolates of Streptococcus pneumoniae having different optochin susceptibilities were recovered from a blood sample of a 2-year-old boy with community-acquired pneumonia. The two isolates were documented to belong to a single clone on the basis of the isolates' identical serotype (23F), antibiograms by the E-test, random amplified polymorphic DNA patterns generated by arbitrarily primed PCR, pulsed-field gel electrophoresis, and restriction fragment length polymorphism of the penicillin-binding protein genes pbp2b and pbp2x.
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