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Sexual dysfunction in multiple sclerosis: II. Correlation analysis.

R Zivadinov1, M Zorzon, A Bosco

  • 1Clinical Neurology, University of Trieste, Trieste, Italy.

Multiple Sclerosis (Houndmills, Basingstoke, England)
|January 5, 2000
PubMed
Summary
This summary is machine-generated.

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Sexual dysfunction is common in multiple sclerosis (MS), linked to physical, psychological, and social factors. Sphincteric dysfunction suggests a common spinal cord cause, but other elements also play a role.

Area of Science:

  • Neuroscience
  • Clinical Neurology
  • Sexual Medicine

Background:

  • Sexual dysfunction is prevalent in multiple sclerosis (MS) patients.
  • The precise clinical presentation and etiology of MS-related sexual dysfunction require further clarification.

Purpose of the Study:

  • To investigate the relationship between sexual dysfunction and various patient and disease characteristics in multiple sclerosis.
  • To explore correlations with disability, neurological impairment, psychological functioning, and cognitive status.

Main Methods:

  • An unselected sample of 108 patients with definite multiple sclerosis was studied.
  • Statistical analysis was performed to identify correlations between sexual dysfunction and multiple variables.

Main Results:

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  • Sexual dysfunction significantly correlated with sphincteric dysfunction, physical disorders, disability, cognitive deterioration, depression, fatigue, and anxiety.
  • Factors such as lower education, older age at onset, primary-progressive disease course, male gender, and unemployment were also associated with sexual dysfunction.
  • A negative correlation was observed with a relapsing-remitting disease course.

Conclusions:

  • The link between sexual and sphincteric dysfunction in MS suggests a common etiology related to spinal cord involvement.
  • Physical, psychological, and sociological factors likely contribute to the multifactorial nature of sexual dysfunction in multiple sclerosis.