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Magnesium: physiology and pharmacology
W J Fawcett1, E J Haxby, D A Male
1Department of Anaesthesia, Royal Surrey County Hospital, Guildford, Surrey, UK.
British Journal of Anaesthesia
|January 5, 2000
Summary
Magnesium plays a key role in obstetrics and is increasingly used in cardiology. Further research will clarify its benefits in treating magnesium deficiency and as a medication.
Area of Science:
- Biochemistry
- Clinical Medicine
- Pharmacology
Background:
- Magnesium has a well-documented role in obstetrics.
- Its application in cardiology is emerging but not fully established.
- Many magnesium-related effects remain controversial.
Purpose of the Study:
- To review the current understanding of magnesium's role in medicine.
- To highlight areas of controversy and ongoing research.
- To project future research directions for magnesium's clinical applications.
Main Methods:
- Literature review of existing studies on magnesium.
- Analysis of current controversies and research gaps.
- Discussion of potential improvements in magnesium measurement and mechanistic understanding.
Main Results:
- Magnesium's role in obstetrics is established.
- Magnesium's role in cardiology is evolving.
- Further research is needed to resolve controversies.
Conclusions:
- Improvements in magnesium measurement and understanding mechanisms are crucial.
- Clinical studies will further elucidate magnesium's therapeutic potential.
- Magnesium's dual role in deficiency treatment and as a pharmacological agent requires continued investigation.