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Diagnostic testing in occupational asthma.

R A Tan1, S L Spector

  • 1California Allergy and Asthma Medical Group, Inc. Los Angeles 90025, USA.

Annals of Allergy, Asthma & Immunology : Official Publication of the American College of Allergy, Asthma, & Immunology
|January 5, 2000
PubMed
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Diagnosing occupational asthma can be difficult, but a key indicator is asthma symptoms improving when away from work. Specific bronchial challenges are the gold standard for confirming this work-related condition.

Area of Science:

  • Occupational Medicine
  • Pulmonology
  • Allergy and Immunology

Background:

  • Occupational asthma diagnosis is challenging due to unclear links between work and symptoms.
  • Accurate diagnosis is crucial given the potential career impact on workers.
  • Initial clues include asthma symptoms that improve when away from the workplace.

Purpose of the Study:

  • To outline diagnostic approaches for occupational asthma.
  • To highlight the importance of identifying work-related triggers for asthma.

Main Methods:

  • Utilizing a history of work-associated asthma symptom improvement outside of work.
  • Employing nonspecific bronchial challenges (e.g., methacholine) to confirm asthma.
  • Conducting specific IgE testing (preferably skin testing) for suspected agents.

Related Experiment Videos

  • Performing serial monitoring of peak expiratory flow rate (PEFR) or forced expiratory volume in 1 second (FEV1) at and away from work.

    • Main Results:

    • Nonspecific bronchial challenges can aid in asthma diagnosis.
    • Specific IgE testing identifies sensitivities to occupational agents.
    • Serial PEFR or FEV1 monitoring differentiates occupational from non-occupational asthma.

    Conclusions:

    • Specific bronchial challenge testing against suspected occupational agents is the definitive diagnostic method.
    • Accurate diagnosis of occupational asthma is essential for worker health and career management.