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Related Experiment Videos

Hypertension control: multifactorial contributions.

J M Neutel1, D H Smith

  • 1Orange County Heart Institute and Research Center, Orange, California 92868, USA.

American Journal of Hypertension
|January 5, 2000
PubMed
Summary
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Hypertension may be part of a larger inherited hypertension syndrome, with cardiovascular risks appearing before high blood pressure. Early detection of this syndrome could prevent related diseases.

Area of Science:

  • Cardiology
  • Genetics
  • Internal Medicine

Background:

  • Hypertension treatment reduces some cardiovascular risks but not all.
  • A new theory proposes hypertension is part of a broader inherited hypertension syndrome.
  • Cardiovascular disease may precede elevated blood pressure in some individuals.

Purpose of the Study:

  • To explore the concept of the hypertension syndrome.
  • To investigate the early manifestations of cardiovascular disease risk factors.
  • To determine if early detection of hypertension syndrome components can prevent cardiovascular disease.

Main Methods:

  • Review of existing epidemiologic studies.
  • Analysis of findings related to inherited risk factors for hypertension.

Related Experiment Videos

  • Examination of early markers associated with cardiovascular disease.

    • Main Results:

    • Normotensive individuals with a family history of hypertension show similar disease processes and prognoses to hypertensives.
    • Inherited abnormalities predispose individuals to hypertension and associated cardiovascular risk factors.
    • Components of hypertension syndrome include elevated lipids, left ventricular hypertrophy, arterial stiffening, insulin resistance, renal, and neuroendocrine changes.

    Conclusions:

    • Hypertension syndrome may be reversible if diagnosed early, potentially before high blood pressure onset.
    • Elevated blood pressure might be a marker for irreversible vascular disease.
    • Early detection of hypertension syndrome components may delay or prevent cardiovascular disease in high-risk patients.