Related Experiment Videos
Penile fibrotic changes after radical retropubic prostatectomy
1Scott Department of Urology, Baylor College of Medicine, Houston, Texas 77030, USA. sciancio@bcm.tmc.edu
BJU International
|January 5, 2000
Summary
Penile fibrotic changes affect 41% of men with erectile dysfunction post-radical retropubic prostatectomy (RRP). Treatment improved outcomes for many, though predictive factors remain elusive.
Area of Science:
- Urology
- Andrology
- Surgical Oncology
Background:
- Radical retropubic prostatectomy (RRP) is a common treatment for prostate cancer.
- Erectile dysfunction (ED) is a known complication following RRP.
- Penile fibrotic changes, such as curvature and plaques, can develop after RRP.
Purpose of the Study:
- To investigate the characteristics of penile fibrotic changes after RRP.
- To assess the response to treatment for these fibrotic changes.
- To identify potential predictive factors for their development.
Main Methods:
- 110 men with ED post-RRP were evaluated for penile fibrotic changes.
- Patients with fibrotic changes received medical therapy and were followed.
- Chart review and interviews were conducted to determine outcomes.
Main Results:
- 41% of men with ED post-RRP exhibited penile fibrotic changes.
- Penile curvature (93%) and palpable plaques (69%) were common presentations.
- 40% of treated men reported improvement, often with vacuum devices or injections.
Conclusions:
- Penile fibrotic changes are a significant, previously underreported issue after RRP.
- No specific predisposing factors were identified in this study.
- Further prospective studies are needed to confirm findings and explore etiology.