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Follicular carcinoma in a functioning struma ovarii
A Bhansali1, V Jain, A Rajwanshi
1Department of Endocrinology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Postgraduate Medical Journal
|January 6, 2000
Summary
This case report details follicular carcinoma within a functioning struma ovarii, presenting as an ovarian mass post-thyroidectomy. The patient successfully managed with surgery, radiotherapy, and L-thyroxine, showing no metastases after four years.
Area of Science:
- Gynecologic Oncology
- Endocrinology
- Pathology
Background:
- Struma ovarii is a rare germ cell tumor containing thyroid tissue.
- Follicular carcinoma in struma ovarii is exceptionally rare, often presenting as an ovarian mass.
- Prior thyroidectomy for benign disease can complicate diagnosis.
Observation:
- A patient with a history of near-total thyroidectomy for a benign lesion presented with an ovarian mass.
- The ovarian mass was diagnosed as a functioning struma ovarii with follicular carcinoma.
- The patient had no prior history suggestive of thyroid malignancy.
Findings:
- Surgical management included bilateral salpingo-oophorectomy.
- Post-operative treatment consisted of radiotherapy and L-thyroxine hormone replacement therapy.
- Follow-up for four years revealed no evidence of distant metastases.
Implications:
- This case highlights the importance of considering ectopic thyroid tissue in ovarian masses, especially in patients with thyroid disease history.
- Multidisciplinary management involving gynecologic oncology, endocrinology, and pathology is crucial.
- Effective treatment strategies include surgery, radiotherapy, and hormone suppression for struma ovarii follicular carcinoma.