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Related Experiment Videos

Multiple anthelmintic resistance in a goat herd.

A M Zajac1, T A Gipson

  • 1Virginia-Maryland Regional College of Veterinary Medicine, Virginia, Polytechnic Institute and State University, Blacksburg 24061, USA. azajac@vt.edu

Veterinary Parasitology
|January 6, 2000
PubMed
Summary

Anthelmintic resistance to common goat dewormers, including ivermectin and benzimidazoles, was confirmed in Haemonchus contortus. Strategic drug rotation and withdrawal showed potential for restoring drug susceptibility.

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Area of Science:

  • Veterinary Parasitology
  • Anthelmintic Resistance
  • Goat Health Management

Background:

  • Anthelmintic resistance poses a significant threat to goat production worldwide.
  • Haemonchus contortus is a major gastrointestinal nematode parasite in small ruminants.
  • Monitoring resistance is crucial for effective parasite control strategies.

Purpose of the Study:

  • To monitor anthelmintic resistance in a goat herd over 30 months.
  • To evaluate the efficacy of different anthelmintic drugs and treatment protocols.
  • To assess the potential for restoring drug susceptibility through strategic drug use.

Main Methods:

  • Fecal egg count reduction test (FECRT) was used to monitor resistance.
  • Resistance to ivermectin, levamisole, and benzimidazoles was assessed.

Related Experiment Videos

  • Parasite cultures identified predominant genera, primarily Haemonchus.

    • Main Results:

    • Resistance to ivermectin, levamisole, and benzimidazoles was detected in Haemonchus contortus.
    • Susceptibility to levamisole returned after a 1-year withdrawal period.
    • A fenbendazole protocol showed fluctuating efficacy, indicating persistent resistance.
    • Haemonchus was the predominant parasite genus identified.

    Conclusions:

    • The study confirmed anthelmintic resistance in a Virginia goat herd.
    • Strategic drug withdrawal can potentially restore susceptibility to certain anthelmintics.
    • Continuous monitoring and adaptive management are essential for controlling resistant parasites.